Rub-in procedure using alcohol-based hand disinfectants to reduce transient skin flora as much as possible to prevent transmission of microorganisms. In Europe, efficacy testing is done in vivo according to EN 1500 that requires the test product’s reduction of microorganisms — measured in log10 steps — to not be significantly lower than the result of the reference procedure. In 2005, the World Health Organization (WHO) launched a global campaign to increase hand hygiene compliance, introducing the 5 Moments for Hand Hygiene. Properly performed hygienic hand disinfection includes both the correct rub-in duration and the correct rub-in technique to avoid gaps in coverage and to achieve the best reduction of microorganisms.
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