Multi-resistant gram-negative (MRGN) bacteria are resistant to different classes of antibiotics, i. e. they are not susceptible to inhibitory antibiotics. According to the definition of the German Commission for Hospital Hygiene and Infection Prevention (KRINKO), pathogens are considered multidrug-resistant if at least three of the four antibiotic classes (acylaminopenicillins, carbapenems, cephalosporins, quinolones) are ineffective. In that case, the term would be “3MRGN”. “4MRGN” means that the gram-negative rods are resistant to all four classes. Bacteria commonly resistant are:
Infection or colonisation with multi-resistant Gram-negative rods require adapted hygiene measures, with barrier and disinfection measures playing an essential role.
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